Back in 1988 the world of sports was shocked to learn that famous Canadian sprinter Ben Johnson, who succeeded in something that was not possible before anyone – to win the hundred-meter race Olympic champion Carl Lewis the previous, was caught on the use of anabolic steroids. Because of this, Johnson has been suspended from competition for years to come, because his doping test showed that the athlete’s blood was found stanozololol. Johnson also selected previously obtained a gold medal and signed a contract worth more than eight million dollars. After a few years, in 1990, he was drafted and adopted by the Act for the control of anabolic steroids and as a result, these substances are classified as requiring special permission for the use of controlled substances.
Partly efficiency in great danger
Stanozolol (Winstrol or as it is called in the trade environment) – is a weak steroid. Weak in terms of opportunities for increasing the muscle mass of athletes who take it, but at the same time and is a very popular and common among athletes and bodybuilders. Immediately after the occurrence Vinistrol marketed only in the form of tablets with low dosage of 2 milligrams or in the form of an aqueous slurry in which one milliliter had only fifty milligrams of active compound. At the same time, this steroid can be found in any dosage and concentration, and release it organizes several brands. Earlier bodybuilders took Vinistrol only before important competitions, because thanks to a substance may rapidly improve relief and muscle density. In 1995 he published a cycle of audio from the magazine Muscle Media 2000, a record of which is devoted to an interview in which the narrator shares with the audience stories about how most enduring and successful runners achieved their success by taking a small dose of Winstrol for the prevention of muscle loss that could arise as a result of catabolism, which is often reinforced after the long runs.
Stanozolol is a chemical compound with the following structure: 17-MITIL 5alfa- androstane (3,2-c) pyrazol-17beta-ol and is classified as an anabolic steroid controlled with its assigned number 302-96-5. Because of anabolic-androgenic impressive ratio refers to the steroid vysokoanabolichnym substances. Paradoxically, at the same time, the effect of it to increase strength and muscle mass is not so big. This surprisingly low efficacy can be explained by the fact that he stanozolol – is rather weak androgen, but far inferior to the effectiveness of testosterone as an anabolic agent. If you compare stanozolol and testosterone, vzzyatye in equal doses, in this comparison stanozolol is clearly losing opponent.
Surprisingly, in spite of their low efficiency, stanozolol still enjoys fairly wide popularity. Perhaps the secret of the popularity of this material lies in its reputation absolutely safe steroid, which, if not stunning, and gives the maximum effect soon, but the body does not cause much harm. Of course, this opinion is erroneous. This steroid, though does not cause severe side effects like other vysokoandrogennye steroids, but still is not completely secure. On the contrary: many experts, having relevant clinical trials, come to the conclusion that stanozolol may be considered the most dangerous steroid that exist in the world today.
So dangerous if stanozolol?
So, what can be believed: that stanozolol is almost safe that steroids are dangerous or hard to find? It should be noted that the effect of the substance is still not fully studied and quite versatile. At first glance, stanozolol should operate on the same principle as that of other similar substances: cause increased aggression, hair loss, acne. Preparations based on vysokoallergennoy form of testosterone, it is the effect and render. But the reality is not quite so out. Since stanozolol is a rather weak androgen, it does not increase the aggressiveness of living beings, but rather suppresses it. These data are confirmed by numerous experiments conducted on animals. Subjects instances become so non-aggressive, that even did not respond to physical provocation by other males who invade their personal territory. These experiments proved that the received stenozol not perceived male gonads (namely the seminal vesicles) as a substance replacing testosterone. Rats that received some time this steroid, eventually began to lose the ability to ejaculate and, eventually, cease to show any sexual behavior. Such reactions, researchers have noticed and females, who under the influence of the hormone estrogen lose their sexual receptivity.
So, judging by the effects from taking steroids, displayed on the behavior, the stanozolol rather be called antiandrogen than androgen. Since most human responses to certain substances are not too different from the reactions of test samples, one can safely assume that people taking stanozolol may have disturbed the function of sexual receptivity, so that they may lose their competitive advantage over other individuals.
In addition to the above effects, the reception of stanozolol, according to numerous reports of experts, can cause blockage of the normal functioning of the brain and the various receptor systems, infringement actions anksiliotikov and antidepressants. Many athletes who took some time steroids, talk about the periods of depression that begins sharply immediately after the completion of the cycle of the drug. But experts who study the issue say that stanozolol is contraindicated for people with high sensitivity to such states. Therefore, in spite of that stanozolol, unlike other steroids, does not cause the appearance of so-called “steroid rage”, it still is quite dangerous for everyone who receives it, but in particular it is dangerous to people with unstable mentality, which, by their nature, have a tendency to commit suicide or have psychological trauma.
If we look at the chemical structure of this species of steroids, it should be noted that it is a derivative of dihydrotestosterone, given steroid. This means that stanozolol is not a substrate of the enzyme aromatase, which is responsible for converting into estrogens (female hormones), the majority of androgen. Very few athletes taking stanozolol, note estrogenic side effects if they used only one drug. However, it would be wrong to say that here the danger from taking stanozolol does not. Through research on laboratory mice, the scientists demonstrated that this steroid has the ability to accelerate puberty in females who are in puberty. To avoid such an effect is obtained only in the case in advance, before the course of stanozolol, the experimental animals taken estrogen blocker. After blocker stanozolol still called early changes of the vagina in the mice, but these changes were fairly minor. It is difficult to argue that for people acting this approach, because the dose used in the experiment, much less those who are often athletes take.
The experiment on mice and the results prompted researchers to hypotheses that stanozolol may acts as agonist for the estrogen receptor as well as the more popular Novaldeks (Tamoxifen). Stanozolol, although not a substrate using aromatase and, because of this, has resistance to estrogen conversion, after all, to some extent stimulates aromatase activity, and hence contributes to the fact that estrogen convert other androgens.
In another experiment, experts have tried to study the effect of stanozolol on skin cells in the laboratory. In this experiment they found that stanozolol, in some cases exhibits unique and unexpected results which can not be explained only by its connection with the hormone testosterone.
One of these results is the ability of the steroid to increase the production of collagen in the skin, enzymes and some prostaglandins. Trying to explain this phenomenon, the experts found that in skin fibroblasts (undeveloped early skin cell) is not replaced by stanozolol (not displaced) nortestosterone (androgen), estradiol (estrogen) or deksametasonom (a derivative of cortisol). Instead substituted steroid progesterone – another female hormone. Progesterone has the ability to displace stanozolol from receptors of skin cells, but it may not cause the same response himself. It turns out that the results of this experiment not only shed light on the effect of stanozolol, but even more confusing situation – is absolutely unclear how valid stanozolol. It may interact with other receptors may interfere in the work of other hormones, and possibly functions as a weak substitute.
No study has not shown that stanozolol – is estrogenic or feminizing connection, this could prove to you most taking the drug. This is not a steroid estrogen and provides an opportunity to seal muscle tissue due to minimize the delay in the body fluid. In the case of the drug very rarely can develop gynecomastia, but if you are taking stanozolol in combination with other agents, its negative impact on the body is much more serious.
Available stanozolol in various forms: it can be found in an oral form and as a solution. Chemicals absolutely identical in both forms, the difference between them is only in the fact that the cost of injection solution is somewhat lower at that concentration, on the contrary, above. Oral administration of stanozolol is possible thanks to the fact that the structure of the drug has a methyl group. This group allows him to become one of the semnadtsatialkilirovannyh steroids, which are widely known by its high hepatotoxicity, which is significantly higher compared to the esters contained in the injectable steroids.
Often overlooked as liver toxicity of stanozolol. Most athletes who take this steroid, confident that he – one of the least toxic substances existing steroid, but this is not so. For years, oral stanozolol actively used in medicine to treat completely different diseases. Even now, still undergoing exploration of new areas for its application. But even if stanozolol has been prescribed by your doctor and you have legally obtained the pharmacy, there is a high risk of serious damage to your liver.
In the course of the various long-term experiments for more than half of the subjects were required lowering dosages or discontinuation of altogether due to a significant increase in liver enzyme levels, which is an indicator of damage at the cellular level. However, most scientists still believe that if you use the right intervention possible to completely get rid of all signs and symptoms of liver damage. That is why stanozolol is often chosen as a safe alternative means for the treatment of certain diseases.
It is obvious that in the use of stanozolol liver cell damage is a common symptom. Accordingly, the higher the dose of the substance, the more serious injuries occur. As a result, research has been detected binding protein that is present in the liver of rats and in the human liver. This protein is specific for stanozolol and other steroid – danazol. Studies have shown that stanozolol is toxic to the liver, but the impact of the highest possible dose of a substance (such as above the recommended four hundred times) on liver cells have not shown that this steriod may cause or develop a cancer of the cells, even if they both will act several different carcinogens.
This does not mean that stanozolol may protect against cancer or its development. These results are not yet confirmed, moreover, with stanozolol can be used, and other chemicals that in the course of these experiments have not been considered. There is also one report, officially published, which describes in detail the development in case of a bodybuilder who took stanozolol, severe liver damage and the appearance of his acute renal failure. This athlete every day for eighty days took fifty milligrams of substance intramuscularly, to use up to an additional fifty milligrams of methandienone. Three weeks after the end of the cycle of drugs young athlete went to the hospital for the qualified help. By this time he has had time to develop jaundice, and the body was no longer able to deal with stress. The general condition of the patient worsened all of the following seven weeks, until the beginning of the act expensive treatment.
Other negative effects from taking stanozolol
The above case, unfortunately, is not the only one of its kind. Even a cursory analysis of the specialized literature is possible to find evidence of these incidents taking stanozolol four heart attacks (two of which – with fatal consequences), one case of bleeding, safe for life and one case of sudden rapid heart rhythm. It should be noted that all these incidents have occurred with young people, often up to thirty years.
Among athletes and body builders have long known that taking stanozolol increases the possibility of a heart attack, or heart attack, because the substance reduces the “good” cholesterol in the blood and increases the concentration of “bad”. Women taking this steroid, can manifest effects of masculinization, can cause serious bleeding (epistaxis from banal and ending with varicose veins of the esophagus, which is life-threatening), it increases the risk of getting injured tendons.
Stanozolol is easily detected in the analysis of hair or urine, and the remnants of the substance stored in the body for several months after completion of the drug. It is proved that this steroid suppresses testosterone production organism lowers the transporter protein androgen.
Stanozolol, more commonly known as Winstrol, it is popular today steroid. Most of the athletes who make it absolutely sure that it does not bring much harm to the body. Despite the fact that stanozolol and shows no apparent risk of strong estrogenic and androgenic side effects, it is not as secure as it seems. There is plenty of evidence that taking this drug negatively affects the work of the various systems of the human body. The results of these studies prove conclusively that the steroid compound mimics the effects of estrogen, decreases libido, may contribute to the emergence and development of various mental disorders, debilitating aggression and sexual function, often causing damage to liver cells, and can cause a fatal outcome.
Typically, bodybuilders take a day to a hundred milligrams of stanozolol, even receiving six to ten milligrams per day is able to cause irreparable damage to your body. Given what is currently known to a huge variety of steroids, many of which have much fewer side effects and risks than stanozolol, if you are going to use this drug, think about it: is it worth it.
You have not tried a solo strombafort on course for a set of qualitative dry weight?